Description

9-(2-Amino-2-Deoxy-α-D-Ribofuranosyl)-9H-Purin-6-Amine is a nucleoside analog with significant biochemical and pharmaceutical relevance. This compound serves as a crucial building block and intermediate in the synthesis of modified nucleotides and oligonucleotides, enabling advanced research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, antiviral drug discovery, and molecular biology applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and repair.
• Oligonucleotide Synthesis: Serves as a modified nucleoside phosphoramidite building block for constructing specialized DNA/RNA sequences.
• Proteomics & Genomics: Employed in the development of probes, labels, and tools for studying gene expression and protein-nucleic acid interactions.
• Antiviral Agent Development: Investigated for its potential activity and as a scaffold for designing drugs targeting viral polymerases.

Basic Information

Product Name	9-(2-Amino-2-Deoxy-α-D-Ribofuranosyl)-9H-Purin-6-Amine
CAS No.	10407-64-4
Molecular Formula	C10H14N6O4
Molecular Weight	282.26 g/mol
Synonyms	2'-Deoxy-2'-aminoadenosine; 2'-Amino-2'-deoxyadenosine; 2'-NH2-dA; Cordycepin analog; 9H-Purin-6-amine, 9-(2-amino-2-deoxy-α-D-ribofuranosyl)-; Adenosine, 2'-amino-2'-deoxy-; 2'-Amino-2'-deoxyadenosine
EINECS	Contact for details

Quality Control

We supply 9-(2-Amino-2-Deoxy-α-D-Ribofuranosyl)-9H-Purin-6-Amine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.