Description

4-Methyl-3-Nitrobenzoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 4-methyl-3-nitrobenzoyl moiety, enabling the construction of complex molecules with specific functionalities. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a substituted benzoyl group.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the nitro and acyl chloride groups facilitate further chemical modifications.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for creating azo dyes and other complex colorants.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers and liquid crystals.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Peptide Coupling Reagent: Can be utilized in peptide synthesis as an activating agent for carboxylic acids.

Basic Information

Product Name	4-Methyl-3-Nitrobenzoyl Chloride
CAS No.	10397-30-5
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	3-Nitro-4-methylbenzoyl chloride; 4-Methyl-3-nitrobenzoic acid chloride; 3-Nitro-p-toluoyl chloride; m-Nitro-p-toluoyl chloride; 2-Methyl-5-nitrobenzoyl chloride; 5-Nitro-2-methylbenzoyl chloride; Benzoic acid, 4-methyl-3-nitro-, chloride
EINECS	233-856-4

Quality Control

Our 4-Methyl-3-Nitrobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.