Description

18,20-Cyclo-20,21-Dihydroxy-4-Pregnen-3-One is a specialized synthetic steroid derivative with a unique cyclopropane ring fused to the pregnane skeleton. This compound serves as a critical advanced intermediate in the synthesis of novel steroid-based pharmaceuticals and research compounds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid hormone analogs and receptor modulators.
• Research & Development: Used in academic and industrial research to study structure-activity relationships (SAR) of modified steroid scaffolds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in steroid analysis.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex steroid molecules.
• Biochemical Probe: Utilized to investigate steroidogenic enzyme interactions and metabolic pathways.

Basic Information

Product Name	18,20-Cyclo-20,21-Dihydroxy-4-Pregnen-3-One
CAS No.	10385-97-4
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	18,20-Cyclo-20,21-dihydroxypregn-4-en-3-one; 20,21-Dihydroxy-18,20-cyclopregnen-3-one; 4-Pregnen-3-one, 18,20-cyclo-20,21-dihydroxy-; Pregn-4-ene-3-one, 18,20-cyclo-20,21-dihydroxy-; 18,20α-Cyclo-20,21-dihydroxypregn-4-en-3-one
EINECS	Contact for details

Quality Control

Our 18,20-Cyclo-20,21-Dihydroxy-4-Pregnen-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.