Description

(9β)-Cholesta-5,7-Dien-3β-Ol CAS NO 10346-44-8 is a high-purity sterol derivative, specifically a dihydroxycholesterol analog, that serves as a critical intermediate in advanced organic synthesis. Its unique conjugated diene structure makes it a valuable precursor for the production of vitamin D analogs, secosteroids, and other biologically active compounds. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on steroid chemistry, drug discovery, and nutraceutical development.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of vitamin D3 (cholecalciferol) and its synthetic analogs.
• Biochemical Research: Used as a standard or reagent in studies of cholesterol metabolism, membrane biology, and steroid hormone pathways.
• Fine Chemical Synthesis: A versatile building block for creating complex secosteroids and other steroidal compounds with modified ring structures.
• Nutraceutical Development: Employed in the research and scaled production of advanced vitamin D supplements and related health products.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and chemical manufacturing.

Basic Information

Product Name	(9β)-Cholesta-5,7-Dien-3β-Ol
CAS No.	10346-44-8
Molecular Formula	C₂₇H₄₄O
Molecular Weight	384.64 g/mol
Synonyms	7-Dehydrocholesterol; Provitamin D3; (3β)-Cholesta-5,7-dien-3-ol; 5,7-Cholestadien-3β-ol; Lathosterol (Note: Lathosterol is 5α-Cholest-7-en-3β-ol, a common mis-association); δ5,7-Cholestadien-3β-ol; NSC 8798; Provitamin D₃
EINECS	233-757-1

Quality Control

Our (9β)-Cholesta-5,7-Dien-3β-Ol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. For long-term storage, keep the material frozen at -20°C. The container should be kept in a cool, dry, and well-ventilated area away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.