Description

Benzyl 4-(Chlorocarbonyl)Tetrahydro-1(2H)-Pyridinecarboxylate is a versatile and high-purity chemical intermediate used in advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both a benzyl-protected carboxylate and a highly reactive acid chloride group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that incorporate the tetrahydro-1(2H)-pyridine scaffold.
• Peptide Mimetics & Conjugation: Serves as a coupling reagent or a protected amino acid analog for creating peptide-like structures and bioconjugates.
• Material Science Research: Employed in the development of specialty polymers and functional organic materials requiring specific piperidine derivatives.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & R&D Laboratories: Utilized in methodological chemistry research for exploring new reactions and catalytic processes involving acid chlorides and protected amines.

Basic Information

Item	Details
Product Name	Benzyl 4-(Chlorocarbonyl)Tetrahydro-1(2H)-Pyridinecarboxylate
CAS No.	10314-99-5
Molecular Formula	C14H16ClNO3
Molecular Weight	281.73 g/mol
Synonyms	Benzyl 4-(chloroformyl)piperidine-1-carboxylate; 1-(Benzyloxycarbonyl)-4-piperidinecarbonyl chloride; 4-(Chlorocarbonyl)-1-piperidinecarboxylic acid benzyl ester; 1-CBZ-4-Piperidinecarbonyl Chloride; N-CBZ-isonipecotyl chloride; 1-N-Carbobenzyloxy-4-piperidinecarbonyl chloride; 4-Carboxy-1-piperidinecarboxylic acid benzyl ester chloride; Z-4-Piperidinecarbonyl Chloride
EINECS	Contact for details

Quality Control

Our Benzyl 4-(Chlorocarbonyl)Tetrahydro-1(2H)-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.