Description

3'-o-Methyl-D-Adenosine is a chemically modified nucleoside derivative, specifically a methylated analog of adenosine. This modification is critical for its role as a biochemical tool and building block in advanced research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector, particularly in areas such as nucleotide chemistry, antiviral research, and the synthesis of modified oligonucleotides.

Application

• Biochemical Research: Used as a reference standard and a key intermediate in studies of enzyme kinetics, methylation processes, and nucleic acid metabolism.
• Antiviral Drug Development: Serves as a crucial precursor or analog in the synthesis of novel nucleoside-based antiviral agents targeting viral polymerases.
• Oligonucleotide Synthesis: Acts as a modified building block for creating specialized oligonucleotides with altered properties for diagnostic assays and therapeutic applications.
• Enzyme Substrate Studies: Employed to investigate the specificity and function of methyltransferases and other enzymes involved in post-transcriptional RNA modification.
• Metabolic Pathway Analysis: Utilized as a tracer or inhibitor compound in metabolic studies to understand cellular signaling and energy pathways.
• Pharmaceutical Intermediates: Functions as a high-purity intermediate in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3'-o-Methyl-D-Adenosine
CAS No.	10300-22-8
Molecular Formula	C11H15N5O4
Molecular Weight	281.27 g/mol
Synonyms	3'-O-Methyladenosine; 3'-Methyladenosine; 9-β-D-Ribofuranosyl-3'-O-methyladenine; Adenosine, 3'-methyl-; 3'-OMe-Ado; 3'-O-Methyl-D-adenosine; 3'-Methyl-D-adenosine; 3'-O-Methyladenosine (D-form)
EINECS	Contact for details

Quality Control

Our 3'-o-Methyl-D-Adenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.