Description

5-Isothiazolecarboxylic Acid is a versatile heterocyclic building block and key synthetic intermediate in organic chemistry. Its unique isothiazole core structure makes it a valuable precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This compound is essential for researchers and manufacturers in the fine chemical, pharmaceutical, and crop protection industries seeking to develop novel active ingredients and advanced molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the isothiazole moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and dyes with specific optical or electronic properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and R&D: A critical starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	5-Isothiazolecarboxylic Acid
CAS No.	10271-85-9
Molecular Formula	C4H3NO2S
Molecular Weight	129.14 g/mol
Synonyms	1,2-Thiazole-5-carboxylic Acid; Isothiazole-5-carboxylic Acid; 5-Carboxyisothiazole; 1,2-Thiazole-5-carboxylic acid (9CI); 5-Isothiazolecarboxylic acid (6CI,7CI); NSC 163063
EINECS	Contact for details

Quality Control

Our 5-Isothiazolecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, which include results from HPLC, NMR, and other relevant analytical methods. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.