Description

2-Amino-1-β-D-Arabinofuranosyl-5-Methyl-4(1H)-Pyrimidinone is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis and study of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of nucleoside-based therapeutics. Our supply is characterized by stringent quality control, ensuring reliability for sensitive applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral and antineoplastic (anticancer) nucleoside drugs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and molecular biology research.
• Antiviral Agent Development: Serves as a core scaffold for developing novel therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Investigated for its potential incorporation into DNA/RNA analogs that inhibit tumor cell proliferation.
• Process Development & Scale-up: Employed in process chemistry for optimizing synthetic routes to complex nucleoside targets.
• Analytical Standard: Provides a high-purity benchmark for quality control (HPLC, LC-MS) in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	2-Amino-1-β-D-Arabinofuranosyl-5-Methyl-4(1H)-Pyrimidinone
CAS No.	10212-31-4
Molecular Formula	C10H15N3O5
Molecular Weight	257.24 g/mol
Synonyms	5-Methyl-2'-deoxycytidine; 5-Methyldeoxycytidine; 5-Methyl-dC; m5dC; 2'-Deoxy-5-methylcytidine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-methylcytosine; 5-Methyl-2'-deoxycytidine (ambiguous, often refers to ribo form); Arabinofuranosyl-5-methylcytosine analog
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-1-β-D-Arabinofuranosyl-5-Methyl-4(1H)-Pyrimidinone is manufactured and tested under a rigorous quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the exacting standards required for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.