Description

2'-Chloro-2'-Deoxycytidine is a halogenated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a versatile building block for the creation of novel therapeutic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for applications in antiviral and anticancer drug discovery, as well as in biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside-based antiviral and anticancer prodrugs.
• Antiviral Research: Used in the development and study of novel compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor for cytostatic agents and compounds designed to interfere with DNA synthesis in cancer cells.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate the function of nucleoside kinases and other metabolic enzymes.
• Prodrug Development: Utilized in the design of masked nucleoside analogs to improve bioavailability and targeting.
• Organic Synthesis: Acts as a chiral starting material for the preparation of more complex, modified nucleosides and oligonucleotides.

Basic Information

Product Name	2'-Chloro-2'-Deoxycytidine
CAS No.	10212-19-8
Molecular Formula	C9H12ClN3O4
Molecular Weight	261.66 g/mol
Synonyms	2'-Chloro-2'-deoxycytidine; 1-(2-Chloro-2-deoxy-β-D-ribofuranosyl)cytosine; 2'-Chloro-2'-deoxycytidine; 2'-Cl-2'-dCyd; 2-Chloro-2'-deoxycytidine; NSC 382198; 2'-Chloro-2'-deoxycytidine (2'-Cl-dC)
EINECS	Contact for details

Quality Control

Our 2'-Chloro-2'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.