Description

Ethyl 2-Ethoxy-2,3,3,3-Tetrafluoropropanoate is a specialized fluorinated ester compound, serving as a valuable building block in advanced chemical synthesis. Its molecular structure, featuring both ethoxy and tetrafluoromethyl groups, makes it a key intermediate for introducing fluorine atoms into target molecules, thereby modifying their physical and biological properties. This compound is essential for R&D and production within the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, or membrane permeability.
• Agrochemical Synthesis: Serves as a key precursor in creating novel herbicides, insecticides, and fungicides, where fluorine incorporation can improve efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Employed in the production of fluorinated components for liquid crystal displays (LCDs) and dielectric materials, leveraging its ability to modify polarity and thermal stability.
• Organic Synthesis Building Block: Acts as a versatile reagent for nucleophilic substitution and condensation reactions to construct complex, fluorinated organic molecules in academic and industrial research.
• Polymer & Surface Modifier: Utilized to introduce fluorine into polymer chains or surface coatings, imparting properties such as oil/water repellency, chemical resistance, and low surface energy.

Basic Information

Product Name	Ethyl 2-Ethoxy-2,3,3,3-Tetrafluoropropanoate
CAS No.	10186-66-0
Molecular Formula	C7H10F4O3
Molecular Weight	218.15 g/mol
Synonyms	2-Ethoxy-2,3,3,3-tetrafluoropropanoic Acid Ethyl Ester; Ethyl 2-Ethoxy-3,3,3-trifluoro-2-(trifluoromethyl)propanoate; Ethyl α-Ethoxy-α-(trifluoromethyl)-β,β,β-trifluoropropionate; Ethyl 2-Ethoxy-3,3,3-trifluoro-2-(trifluoromethyl)propionate; Tetrafluoroethyl ethoxypropanoate; EETFPP; CAS 10186-66-0
EINECS	Contact for details

Quality Control

Our Ethyl 2-Ethoxy-2,3,3,3-Tetrafluoropropanoate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from strong bases and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.350 - 1.370 @ 20°C
Density	1.25 - 1.35 g/mL @ 25°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.