Description

Ethyl 2-(Chloromethyl)Isonicotinate is a versatile and high-value heterocyclic building block, specifically an ester-substituted pyridine derivative. Its molecular structure, featuring both a reactive chloromethyl group and an ethyl ester, makes it a critical intermediate for synthesizing complex pharmacologically active compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries who require reliable, high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Building block for synthesizing functionalized pyridine polymers and advanced organic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom molecule production.
• Academic and R&D Laboratories: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	Ethyl 2-(Chloromethyl)Isonicotinate
CAS No.	10177-22-7
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	Ethyl 2-(chloromethyl)isonicotinate; Ethyl 2-(Chloromethyl)-4-pyridinecarboxylate; 4-Pyridinecarboxylic acid, 2-(chloromethyl)-, ethyl ester; 2-(Chloromethyl)isonicotinic acid ethyl ester; Isonicotinic acid, 2-(chloromethyl)-, ethyl ester; Ethyl 2-(chloromethyl)pyridine-4-carboxylate; 2-(Chloromethyl)-4-(ethoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Chloromethyl)Isonicotinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed due to the compound's sensitivity to moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.