Description

Methyl 6-Formylnicotinate is a high-purity, versatile chemical building block featuring both an aldehyde and an ester functional group on a pyridine ring. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive formyl group for derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the design and synthesis of organic semiconductors, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Methyl 6-Formylnicotinate
CAS No.	10165-86-3
Molecular Formula	C8H7NO3
Molecular Weight	165.15 g/mol
Synonyms	6-Formylnicotinic Acid Methyl Ester; Methyl 6-Formylpyridine-3-carboxylate; 3-Pyridinecarboxylic Acid, 6-Formyl-, Methyl Ester; 6-Carbomethoxynicotinaldehyde; 6-Methoxycarbonylnicotinaldehyde; Methyl 5-Formylnicotinate (common numbering variation); Nicotinic acid, 6-formyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Formylnicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.