Description

3β,11α,12β,14β-Tetrahydroxypregn-5-En-20-One 11-Acetate is a high-purity steroid derivative and a key synthetic intermediate in pharmaceutical research and development. This compound matters for its role in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and reference standards. It is primarily needed by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex steroid hormones and related APIs.
• Reference Standard: Used as an analytical standard in quality control (QC) and research laboratories for method development and compound identification.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding assays.
• Process Development: Serves as a starting material or intermediate for optimizing scalable synthetic routes in process chemistry.
• Fine Chemical Synthesis: Utilized in the custom synthesis of specialized steroid derivatives for academic and industrial research projects.

Basic Information

Product Name	3β,11α,12β,14β-Tetrahydroxypregn-5-En-20-One 11-Acetate
CAS No.	10163-82-3
Molecular Formula	C23H34O6
Molecular Weight	406.52 g/mol
Synonyms	11α,14β,21-Trihydroxy-3β-(acetyloxy)pregn-5-en-20-one; 3β,11α,12β,14β-Tetrahydroxypregn-5-en-20-one 11-acetate; 11-Acetoxy-3β,12β,14β-trihydroxypregn-5-en-20-one; Pregn-5-ene-3β,11α,12β,14β-tetrol-20-one 11-acetate; 3β-Acetoxy-11α,12β,14β-trihydroxypregn-5-en-20-one; 11α-Acetoxy-3β,12β,14β-trihydroxypregn-5-en-20-one; Tetrahydroxypregnenolone 11-acetate
EINECS	Contact for details

Quality Control

Our 3β,11α,12β,14β-Tetrahydroxypregn-5-En-20-One 11-Acetate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing lot-specific results are available upon request. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.