Description

1Alpha-Hydroxycorticosterone is a synthetic corticosteroid derivative, a key intermediate in the synthesis of more complex steroid-based pharmaceuticals. This compound matters for its role in enabling the research and development of novel anti-inflammatory and immunosuppressive agents. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced corticosteroid drugs.
• Biochemical Research: Used as a reference standard or precursor in studies of steroid hormone metabolism and receptor activity.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create specialized steroid analogs for biological testing.
• Academic & Contract Research: Serves as a valuable reagent for universities and CROs investigating inflammation pathways and endocrine function.

Basic Information

Product Name	1Alpha-Hydroxycorticosterone
CAS No.	10163-49-2
Molecular Formula	C₂₁H₃₀O₅
Molecular Weight	362.46 g/mol
Synonyms	1α-Hydroxycorticosterone; 1α-Hydroxy-11-deoxycorticosterone; 1α-Hydroxy-21-hydroxy-4-pregnene-3,20-dione; 1α,21-Dihydroxypregn-4-ene-3,20-dione; 11-Deoxy-1α-hydroxycorticosterone
EINECS	Contact for details

Quality Control

Our 1Alpha-Hydroxycorticosterone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider sealing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.