Description

6-Hydroxy-5,6-Dihydrouridine is a modified nucleoside, specifically a derivative of uridine, where a hydroxyl group is added at the 6-position of the pyrimidine ring. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a natural component of transfer RNA (tRNA), influencing RNA stability and function. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, RNA biology studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and reagent in the study of RNA modification, structure, and function.
• Pharmaceutical Development: Serves as a key intermediate or building block in the synthesis of novel nucleoside-based drugs and prodrugs.
• Diagnostic Reagents: Can be employed in the development of diagnostic kits and assays for detecting specific RNA modifications or related enzymes.
• Enzymology Studies: Used as a substrate to investigate the activity and kinetics of RNA-modifying enzymes, such as hydroxylases.
• Academic Research: Essential for universities and labs focusing on molecular biology, genetics, and post-transcriptional gene regulation.

Basic Information

Product Name	6-Hydroxy-5,6-Dihydrouridine
CAS No.	10141-65-8
Molecular Formula	C9H14N2O7
Molecular Weight	262.22 g/mol
Synonyms	5,6-Dihydro-6-hydroxyuridine; 6-Hydroxy-5,6-dihydrouridine; HO6Urd; 6-HO-DHU; 6-Hydroxyuridine (dihydro); 6-Hydroxy-5,6-dihydro-uridine; Uridine, 5,6-dihydro-6-hydroxy-; 6-Hydroxy-5,6-dihydrouridine (HO6U)
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-5,6-Dihydrouridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.