Description

Methyl 3-Hydroxy-5-Isoxazolecarboxylate is a versatile heterocyclic building block and key synthetic intermediate in organic chemistry. Its unique isoxazole core functionalized with both a hydroxyl and an ester group makes it a valuable precursor for the development of more complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. It serves as a critical starting material for synthesizing various active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and possessing antimicrobial or anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isoxazole ring contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for creating complex heterocyclic compounds, dyes, and functional materials used in various high-tech applications.
• Academic & Industrial Research: Employed in medicinal chemistry and chemical biology research for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: The hydroxyl and carboxylate groups can be utilized to create chelating ligands for metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	Methyl 3-Hydroxy-5-Isoxazolecarboxylate
CAS No.	10068-07-2
Molecular Formula	C5H5NO4
Molecular Weight	143.10 g/mol
Synonyms	Methyl 3-hydroxy-1,2-oxazole-5-carboxylate; 5-Carbomethoxy-3-hydroxyisoxazole; 3-Hydroxy-5-methoxycarbonylisoxazole; Methyl 3-hydroxyisoxazole-5-carboxylate; 3-Hydroxy-5-isoxazolecarboxylic acid methyl ester; 5-Methoxycarbonyl-3-hydroxyisoxazole; 1,2-Oxazole-5-carboxylic acid, 3-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Hydroxy-5-Isoxazolecarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support your research and production needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.