Description

(8α)-3-Methoxyestra-1,3,5(10),14-Tetren-17-One is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its specific structural configuration, which makes it a crucial building block for the synthesis of more complex steroidal molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of specialized steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for exploring new drug candidates and metabolic pathways.
• Hormone Analog Synthesis: Serves as a foundational structure for developing novel hormone analogs and receptor modulators.
• Biochemical Research: Employed in academic and industrial labs to study steroid biochemistry, enzyme interactions, and metabolic processes.
• Process Development: Used in scaling up and optimizing synthetic routes for steroidal compounds in pilot plants and manufacturing settings.

Basic Information

Product Name	(8α)-3-Methoxyestra-1,3,5(10),14-Tetren-17-One
CAS No.	10003-02-8
Molecular Formula	C20H24O2
Molecular Weight	296.40 g/mol
Synonyms	8α-3-Methoxyestra-1,3,5(10),14-tetraen-17-one; 3-Methoxy-8α-estra-1,3,5(10),14-tetraen-17-one; 8α-Estra-1,3,5(10),14-tetraene-3,17-diol 3-methyl ether; 17-Oxo-8α-estra-1,3,5(10),14-tetraen-3-yl methyl ether; 8α-Methoxyestra-1,3,5(10),14-tetraen-17-one
EINECS	Contact for details

Quality Control

Our (8α)-3-Methoxyestra-1,3,5(10),14-Tetren-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.