Description

3α-Hydroxy-5α-Androstane-17β-Carboxylic Acid Methyl Ester is a high-purity steroid derivative and a key synthetic intermediate in organic chemistry. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in steroid chemistry, hormone research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard and a starting material in academic and industrial research focused on steroid metabolism and receptor activity.
• Biochemical Synthesis: Serves as a chiral building block for constructing complex natural products and analogs in medicinal chemistry programs.
• Hormone Analog Development: Employed in the research and development of novel androgen and corticosteroid analogs with potential therapeutic applications.

Basic Information

Product Name	3α-Hydroxy-5α-Androstane-17β-Carboxylic Acid Methyl Ester
CAS No.	10002-85-4
Molecular Formula	C21H34O3
Molecular Weight	334.50 g/mol
Synonyms	3α-Hydroxy-5α-androstane-17β-carboxylic acid methyl ester; Methyl 3α-hydroxy-5α-androstane-17β-carboxylate; 17β-Carbomethoxy-5α-androstan-3α-ol; 3α-Hydroxy-17β-methoxycarbonyl-5α-androstane; Androstane-17β-carboxylic acid, 3α-hydroxy-, methyl ester, (5α)-
EINECS	Contact for details

Quality Control

Our 3α-Hydroxy-5α-Androstane-17β-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.