Description

4-(3-Fluorophenyl)-1,2,3,6-Tetrahydropyridine is a versatile fluorinated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic incorporation of a fluorine atom and a tetrahydropyridine scaffold, which are key motifs for modulating the biological activity and physicochemical properties of target molecules. This high-purity building block is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and psychiatric disorder research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand & Catalyst Precursor: Can be utilized to develop novel ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: An important compound for investigating the effects of fluorination on molecular conformation and reactivity.

Basic Information

Product Name	4-(3-Fluorophenyl)-1,2,3,6-Tetrahydropyridine
CAS No.	1978-60-5
Molecular Formula	C11H12FN
Molecular Weight	177.22 g/mol
Synonyms	4-(3-Fluorophenyl)-1,2,3,6-tetrahydropyridine; 3-Fluoro-4-(1,2,3,6-tetrahydropyridin-4-yl)benzene; 1,2,3,6-Tetrahydro-4-(3-fluorophenyl)pyridine; 4-(m-Fluorophenyl)-1,2,3,6-tetrahydropyridine; 3-Fluorophenyl-1,2,3,6-tetrahydropyridine; 4-(3-Fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride (salt form); 1978-60-5 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorophenyl)-1,2,3,6-Tetrahydropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.