Description

20-Azacholesterol is a synthetic steroidal analog where a nitrogen atom replaces a carbon atom in the cholesterol backbone, creating a unique azasteroid structure. This modification is of significant interest in biochemical and pharmaceutical research for studying cholesterol metabolism, enzyme inhibition, and as a potential precursor for novel therapeutic agents. It serves as a critical research chemical for scientists in pharmaceutical development, metabolic disease research, and steroid chemistry.

Application

• Biochemical Research: Used as a molecular probe to investigate cholesterol biosynthesis pathways and the mechanisms of related enzymes like sterol reductases.
• Pharmaceutical Intermediates: Serves as a key synthetic building block for the development of novel azasteroid-based drug candidates targeting metabolic disorders.
• Enzyme Inhibition Studies: Acts as a potential inhibitor for enzymes involved in sterol metabolism, useful for in vitro assay development and mechanism elucidation.
• Academic & Industrial R&D: Employed in universities and corporate R&D labs for fundamental studies on steroid structure-activity relationships (SAR).
• Reference Standard: Can be utilized as an analytical standard in chromatographic methods (HPLC, GC) for quality control and method validation in related synthetic processes.

Basic Information

Product Name	20-Azacholesterol
CAS No.	1973-59-7
Molecular Formula	C27H47N
Molecular Weight	385.68 g/mol
Synonyms	20-Aza-5-cholesten-3β-ol; 3β-Hydroxy-20-azacholest-5-ene; 20-Azacholest-5-en-3β-ol; Azacholesterol; 20-Norcholest-5-en-3β-ylamine (derivative); 20-Aza-5-cholestene-3β-ol; 20-Azacholest-5-ene-3β-ol
EINECS	Contact for details

Quality Control

Our 20-Azacholesterol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research specifications. For custom purity grades or specific impurity profiles, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.