Description

Thymidylyl(3'->5')Thymidine Ammonium Salt is a high-purity nucleotide derivative, specifically a thymidine dinucleotide, essential for advanced biochemical research and development. This compound serves as a critical building block and reference standard in the synthesis and study of oligonucleotides, DNA, and related nucleic acid structures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications in molecular biology, antisense therapy development, and analytical method validation.

Application

• Oligonucleotide Synthesis: Acts as a key intermediate or phosphoramidite precursor in the solid-phase synthesis of DNA strands and probes.
• Biochemical Research: Used as a substrate or standard in enzymatic studies involving DNA polymerases, ligases, and nucleases.
• Pharmaceutical Development: Serves as a starting material or reference compound in the R&D of antisense oligonucleotides, aptamers, and other nucleic acid-based therapeutics.
• Diagnostic Reagents: Employed in the formulation of primers, probes, and controls for PCR and other molecular diagnostic assays.
• Analytical Standards: Provides a high-purity reference material for quality control and method development in HPLC, LC-MS, and other analytical techniques.
• Academic Research: Fundamental tool for studying DNA structure, stability, and hybridization kinetics in university and institutional laboratories.

Basic Information

Product Name	Thymidylyl(3'->5')Thymidine Ammonium Salt
CAS No.	1969-54-6
Molecular Formula	C20H29N5O13P2 • xNH3
Molecular Weight	Contact for details
Synonyms	dTpdT Ammonium Salt; Thymidylyl(3'-5')thymidine ammonium; TpT ammonium salt; Thymidine 3'-5'-cyclic monophosphate ammonium salt (related); 5'-Thymidylic acid, 3'-ester with thymidine, ammonium salt; pdTpT ammonium salt; DNA dimer T-T ammonium salt; Oligonucleotide d(TpT) ammonium salt
EINECS	Contact for details

Quality Control

Our Thymidylyl(3'->5')Thymidine Ammonium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay	≥ 90% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.