Description

16Beta-Methyl-16Alpha,17Alpha-Epoxypregnenolone is a high-purity, synthetic steroid derivative and a key pharmaceutical intermediate. This compound is valued for its specific stereochemistry, which makes it a crucial building block in the synthesis of more complex, biologically active steroid molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced corticosteroid and other steroidal APIs (Active Pharmaceutical Ingredients).
• Steroid Research & Development: Used as a reference standard and a starting material in medicinal chemistry for exploring new drug candidates with anti-inflammatory or hormonal activity.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for creating specialized steroid analogs in laboratory and pilot-scale production.
• Biochemical Studies: Serves as a tool compound in metabolic pathway research and for studying steroid hormone receptor interactions.

Basic Information

Product Name	16Beta-Methyl-16Alpha,17Alpha-Epoxypregnenolone
CAS No.	1922-48-1
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	16β-Methyl-16α,17α-epoxypregnenolone; 16β-Methyl-16α,17α-oxidopregn-5-en-3β-ol-20-one; (3β)-16β-Methyl-16α,17α-epoxypregn-5-en-20-one-3-ol; 16β-Methyl-16α,17α-epoxy-3β-hydroxypregn-5-en-20-one; Pregnenolone, 16β-methyl-16α,17α-epoxy-; 16β-Methyl-16α,17α-epoxy-5-pregnen-3β-ol-20-one
EINECS	Contact for details

Quality Control

Our 16Beta-Methyl-16Alpha,17Alpha-Epoxyprenolone is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.