Description

9-Fluoro-11Beta-Hydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its precise molecular structure, which is engineered for the development of potent corticosteroid and anti-inflammatory APIs. This compound is essential for R&D and production teams in the pharmaceutical and fine chemical industries, particularly those focused on developing next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent corticosteroid drugs, such as dexamethasone and betamethasone derivatives.
• Active Pharmaceutical Ingredient (API) Development: Used in research and development for creating novel anti-inflammatory and immunosuppressive medications.
• Steroid Chemistry Research: Serves as a reference standard and a starting material for academic and industrial research in steroid hormone analogs.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific fluorinated and hydroxylated functionalities into complex molecules.
• Veterinary Pharmaceutical Manufacturing: Used in the production of anti-inflammatory treatments for animal health applications.

Basic Information

Product Name	9-Fluoro-11Beta-Hydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione
CAS No.	1895-19-8
Molecular Formula	C₂₂H₂₉FO₄
Molecular Weight	376.46 g/mol
Synonyms	9α-Fluoro-11β-hydroxy-6α-methylpregna-1,4-diene-3,20-dione; 9-Fluoro-11β-hydroxy-6α-methyl-1,4-pregnadiene-3,20-dione; 6α-Methyl-9α-fluoro-11β-hydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-11β-hydroxy-6α-methyl-1,4-pregnadiene-3,20-dione; Dexamethasone Intermediate; Betamethasone Related Compound; Fludrocortisone Acetate Intermediate; 1895-19-8
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11Beta-Hydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.