Description

21-Deoxycortisone is a synthetic steroid derivative of significant interest in pharmaceutical research and development. This compound serves as a key intermediate in the synthesis of more complex corticosteroid molecules, offering a crucial building block for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for corticosteroid medications.
• Biochemical Research: Used as a reference standard and tool compound in studies investigating steroid hormone biosynthesis, metabolism, and receptor interactions.
• Metabolic Pathway Studies: Employed in laboratory settings to explore and map enzymatic pathways related to cortisol and cortisone production.
• Process Development: Serves as a starting material for process chemists optimizing scalable and cost-effective manufacturing routes for steroid-based drugs.

Basic Information

Product Name	21-Deoxycortisone
CAS No.	1882-82-2
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	11β,17α,21-Trihydroxypregn-4-ene-3,20-dione; 11β,17α,21-Trihydroxyprogesterone; 21-Desoxycortisone; Reichstein's Substance D; 11β,17α-Dihydroxy-21-desoxypregn-4-ene-3,20-dione
EINECS	217-527-1

Quality Control

Our 21-Deoxycortisone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical manufacturing, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect the product from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.