Description

Psicofuranine is a naturally occurring nucleoside antibiotic with significant biological activity. This compound is valued in research and development for its unique mechanism of action as a glutamine antagonist and its role in studying purine metabolism. It serves as a critical biochemical tool and a potential lead compound for pharmaceutical innovation. Key industries requiring this material include pharmaceutical R&D, academic research institutions, and biotechnology companies focused on metabolic studies and antibiotic discovery.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the investigation of novel antibiotics and metabolic inhibitors.
• Biochemical Research: Utilized as a specific inhibitor of GMP synthetase in studies of purine nucleotide biosynthesis and glutamine-dependent enzymatic pathways.
• Antimicrobial Studies: Serves as a model compound for researching the structure-activity relationships of nucleoside antibiotics and their mechanisms against various microorganisms.
• Academic & Institutional Laboratories: Employed in teaching and advanced research on antibiotic biosynthesis, isolation, and mode of action.
• Biotechnology: Potential use in developing screening assays and exploring its antitumor or antiparasitic properties in early-stage discovery programs.

Basic Information

Product Name	Psicofuranine
CAS No.	1874-54-0
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	Angustmycin A; Decoyinine; 9-β-D-Psicofuranosyladenine; 6-Amino-9-β-D-psicofuranosyl-9H-purine; Psicofuranin; NSC-32946; Antibiotic U-9586; Psicofuranine (Angustmycin A)
EINECS	217-502-5

Quality Control

Our Psicofuranine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and reliability for research applications. We provide comprehensive analytical data including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting key parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with standards suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.