Description

2-Hydroxyadenosine is a modified nucleoside derivative of adenosine, featuring a hydroxyl group at the 2' position of the ribose sugar. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex nucleoside analogs and pharmaceutical agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleotide chemistry, antiviral research, and the development of novel therapeutic compounds. The product is supplied as a high-purity material to ensure reliable and reproducible results in sensitive applications.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic studies and metabolic pathway investigations.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of antiviral and anticancer nucleoside analogs.
• Nucleotide Chemistry: Employed in research focused on RNA structure, function, and modification due to its altered sugar moiety.
• Diagnostic Reagent Development: Acts as a component in the formulation of assays and kits for research purposes.
• Enzyme Inhibition Studies: Investigated for its potential to modulate the activity of adenosine-metabolizing enzymes.

Basic Information

Product Name	2-Hydroxyadenosine
CAS No.	1818-71-9
Molecular Formula	C10H13N5O5
Molecular Weight	283.24 g/mol
Synonyms	2'-Hydroxyadenosine; Adenosine, 2'-hydroxy-; 9-β-D-Ribofuranosyl-2-hydroxyadenine; 2'-OH-Ado; 2-Hydroxyadenosine; 2'-Deoxy-2'-hydroxyadenosine
EINECS	Contact for details

Quality Control

Our 2-Hydroxyadenosine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Standard quality parameters include identification by spectroscopic methods, purity assay by HPLC, and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed and desiccated after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.