Description

5α-Estrane-3β,17β-Diol CAS NO 1816-75-7 is a high-purity steroid derivative belonging to the estrane class, serving as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. This compound is valued for its defined stereochemistry and structural integrity, which are essential for producing consistent and reliable results in sensitive applications. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the production of steroid-based APIs, reference standards, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and hormones.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies, receptor binding assays, and enzymatic research.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for creating novel steroid derivatives with potential therapeutic activity.

Basic Information

Product Name	5α-Estrane-3β,17β-Diol
CAS No.	1816-75-7
Molecular Formula	C₁₈H₃₀O₂
Molecular Weight	278.43 g/mol
Synonyms	5α-Estrane-3β,17β-diol; 3β,17β-Dihydroxy-5α-estrane; Estrane-3β,17β-diol (5α); NSC 121773; 3β,17β-Dihydroxy-5α-estran-17α-yl; 5α-Estran-3β,17β-diol
EINECS	Contact for details

Quality Control

Our 5α-Estrane-3β,17β-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for research and synthesis use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.