Description

Cytosine, 1-Oxide (7Ci,8Ci) is a chemically modified nucleobase derivative, specifically an N-oxide of cytosine. This compound is of significant interest in advanced pharmaceutical research and organic synthesis, serving as a key intermediate or building block. It is primarily utilized by research institutions and chemical manufacturers focused on developing novel nucleoside analogs, prodrugs, and other bioactive molecules. The product is supplied with a CAS Registry Number of 1806-62-8.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies investigating DNA/RNA modification, oxidation damage, and the biological activity of nucleobase derivatives.
• Organic Synthesis: Serves as a specialized precursor for the preparation of more complex heterocyclic compounds and labeled compounds.
• Prodrug Development: Investigated for its potential in creating masked or activated forms of cytosine-based therapeutics.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	Cytosine, 1-Oxide (7Ci,8Ci)
CAS No.	1806-62-8
Molecular Formula	C4H5N3O2
Molecular Weight	127.10 g/mol
Synonyms	1-Oxocytosine; Cytosine 1-Oxide; Cytosine N-Oxide; 4-Amino-2-oxo-1,2-dihydropyrimidine 1-oxide; 4-Aminopyrimidine-2(1H)-one 1-oxide; 2-Hydroxy-4-aminopyrimidine 1-oxide; 4-Amino-1-hydroxypyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our Cytosine, 1-Oxide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.