Description

2,2,2-Trifluoro-1-Naphthalen-2-Yl-Ethanone is a high-purity fluorinated aromatic ketone building block. This compound is valued for its unique trifluoromethyl ketone moiety, which imparts significant electronic and steric properties critical for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals with tailored optical and electronic properties.
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in organic molecules.

Basic Information

Product Name	2,2,2-Trifluoro-1-Naphthalen-2-Yl-Ethanone
CAS No.	1800-42-6
Molecular Formula	C₁₂H₇F₃O
Molecular Weight	224.18 g/mol
Synonyms	2,2,2-Trifluoro-1-(2-naphthyl)ethanone; 2',2',2'-Trifluoro-2-acetonaphthone; 2-Acetylnaphthalene Trifluoromethyl Ketone; 2-Naphthyl Trifluoroacetyl Ketone; 1-(Naphthalen-2-yl)-2,2,2-trifluoroethanone; α,α,α-Trifluoro-2-acetonaphthone; 2-(Trifluoroacetyl)naphthalene; 2-Naphthoyl Trifluoromethane
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-Naphthalen-2-Yl-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.