Description

Cytosine Hydrochloride is the hydrochloride salt of the essential nucleobase cytosine, a fundamental building block of nucleic acids. This high-purity derivative is critical for ensuring precise stoichiometry and enhanced stability in sensitive biochemical synthesis and research applications. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for the synthesis of nucleoside analogs, oligonucleotides, and as a key raw material in antiviral and anticancer drug development.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of antiviral drugs (e.g., cytarabine) and other nucleoside-based therapeutics.
• Oligonucleotide Synthesis: Used in solid-phase synthesis for the production of DNA and RNA strands for research, diagnostics, and therapeutic applications.
• Biochemical Research: Serves as a standard and reagent in enzymatic studies, metabolic pathway analysis, and molecular biology experiments.
• Cell Culture Media: Incorporated as a defined component in specialized cell culture formulations and microbiological media.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and other chromatographic methods.

Basic Information

Product Name	Cytosine Hydrochloride
CAS No.	1784-08-3
Molecular Formula	C4H6N3O·HCl
Molecular Weight	147.57 g/mol
Synonyms	4-Aminopyrimidin-2(1H)-one hydrochloride; 2-Oxo-4-amino-1,2-dihydropyrimidine hydrochloride; Cytosine HCl; 6-Amino-2(1H)-pyrimidinone hydrochloride; 4-Amino-2-hydroxypyrimidine hydrochloride
EINECS	217-235-8

Quality Control

Our Cytosine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances and residual solvents, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.