Description

Iododeoxyuridylate CAS NO 1763-02-6 is a modified nucleoside analog of significant biochemical and pharmaceutical interest. This compound serves as a critical building block and research tool in the development of antiviral and anticancer agents, particularly those targeting DNA synthesis. It is essential for researchers and manufacturers in the fields of nucleic acid chemistry, medicinal chemistry, and life science research. Our supply ensures high purity and batch-to-batch consistency for reliable experimental and developmental outcomes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and antineoplastic (anticancer) nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving thymidylate synthase and other nucleotide-metabolizing enzymes.
• Antiviral Agent Development: Serves as a core structure for researching compounds active against DNA viruses, such as herpesviruses.
• Radiopharmaceuticals: Potential precursor for iodine-125 or iodine-131 labeled compounds used in diagnostic imaging or targeted radiotherapy.
• Molecular Biology Probe: Can be incorporated into oligonucleotides to study DNA-protein interactions or as a marker.
• Life Science Reagent: Supplied to manufacturers of high-purity biochemicals and assay kits for research use.

Basic Information

Product Name	Iododeoxyuridylate
CAS No.	1763-02-6
Molecular Formula	C9H11IN2O8P
Molecular Weight	433.07 g/mol
Synonyms	5-Iodo-2'-deoxyuridylic acid; 5-Iodo-2'-deoxyuridine 5'-monophosphate; 5-Iododeoxyuridine 5'-monophosphate; Idoxuridine monophosphate; IUdR 5'-monophosphate; 5-Iodo-dUMP; 5-Iododeoxyuridylate; 5-Iodo-2'-deoxyuridine 5'-(dihydrogen phosphate)
EINECS	217-173-8

Quality Control

Our Iododeoxyuridylate is manufactured under strict quality systems to ensure it meets the exacting standards required for pharmaceutical research and development. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.