Description

2,2-Bis(Trifluoromethyl)Propionyl Fluoride is a highly reactive and versatile fluorinated building block essential for advanced chemical synthesis. Its unique structure, featuring two trifluoromethyl groups, makes it a critical intermediate for introducing perfluoroalkyl moieties into target molecules. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require fluorinated components for efficacy.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier for creating high-performance polymers with exceptional chemical resistance, thermal stability, and low surface energy.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated liquid crystals and dielectric fluids for electronics applications.
• Organic Synthesis Reagent: Acts as a potent acylating agent and a source of the -C(CF3)2CO- group in complex organic transformations for fine chemicals.

Basic Information

Product Name	2,2-Bis(Trifluoromethyl)Propionyl Fluoride
CAS No.	1735-87-1
Molecular Formula	C5H3F7O
Molecular Weight	212.07 g/mol
Synonyms	Perfluoroisobutyryl Fluoride; 2,2-Bis(trifluoromethyl)propanoyl Fluoride; Pentafluoropropionic Acid, Trifluoromethyl- Trifluoroanhydride; Hexafluoroisobutyryl Fluoride; 3,3,3-Trifluoro-2-(trifluoromethyl)propanoyl Fluoride; PFIBF; 1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)propane-2-carbonyl Fluoride
EINECS	217-082-8

Quality Control

Every batch of 2,2-Bis(Trifluoromethyl)Propionyl Fluoride is manufactured and tested under stringent quality management systems to ensure consistency and reliability for your critical processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and amines. Due to its highly volatile and reactive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain purity and prevent moisture ingress. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.