Description

3-Methyl-5-Phenylisothiazole is a versatile heterocyclic organic compound featuring a phenyl-substituted isothiazole core. This specialized chemical building block is valued for its role in advanced organic synthesis and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting neurological or anti-inflammatory pathways.
• Agrochemical Synthesis: Serves as a core structure for developing novel fungicides, herbicides, and insecticides with enhanced efficacy.
• Material Science Research: Investigated as a precursor or dopant for organic semiconductors, conductive polymers, and advanced photonic materials.
• Ligand and Catalyst Development: Used to synthesize novel nitrogen-sulfur containing ligands for transition metal catalysis in fine chemical production.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized heterocyclic dyes and colorants.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	3-Methyl-5-Phenylisothiazole
CAS No.	1732-45-2
Molecular Formula	C10H9NS
Molecular Weight	175.25 g/mol
Synonyms	5-Phenyl-3-methylisothiazole; 3-Methyl-5-phenyl-1,2-thiazole; 5-Phenyl-3-methyl-1,2-thiazole; Isothiazole, 3-methyl-5-phenyl-; 3-Methyl-5-phenyl-δ²-isothiazoline; 1732-45-2; NSC 163082
EINECS	217-069-5

Quality Control

Our 3-Methyl-5-Phenylisothiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.