Description

4-Iodobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the 4-iodobenzoyl moiety, a key functional group for constructing complex molecules and facilitating further cross-coupling reactions. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring halogenated aromatic structures.
• Liquid Crystal & OLED Materials: Serves as a building block for creating iodinated aromatic cores in electronic and photonic materials for displays.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Peptide & Protein Modification: Employed as an acylating agent to modify amino acids, peptides, or other biomolecules for research and diagnostic purposes.
• Polymer Chemistry: Monomer for synthesizing specialty polyamides, polyesters, and other high-performance polymers with unique thermal and optical properties.
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Iodobenzoyl Chloride
CAS No.	1711-02-0
Molecular Formula	C7H4ClIO
Molecular Weight	266.46 g/mol
Synonyms	p-Iodobenzoyl chloride; 4-Iodobenzoic acid chloride; Benzoic acid, 4-iodo-, chloride; Iodobenzoyl chloride; 4-Iodobenzoylchloride; p-Iodobenzoic acid chloride; 4-Iodo-benzoyl chloride; 1711-02-0 (CAS)
EINECS	216-969-7

Quality Control

Our 4-Iodobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and bases. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.