Description

4-Chloro-3-Methylpyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production rely on this high-purity intermediate to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacturing of advanced pesticides and herbicides, where the chloromethylpyridine moiety contributes to biological efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of functional organic materials, including liquid crystals and electronic chemicals.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and process chemistry optimization in laboratory settings.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	4-Chloro-3-Methylpyridine
CAS No.	1681-36-3
Molecular Formula	C6H6ClN
Molecular Weight	127.57 g/mol
Synonyms	3-Methyl-4-chloropyridine; 4-Chloro-3-picoline; 4-Chloro-3-methylpyridine; 1681-36-3; 4-Chloro-3-methyl-pyridine; 3-Methyl-4-chloro-pyridine; 4-Chloro-3-methylpyridine (9CI)
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.