Description

Cholesteryl Hemisuccinate CAS NO 1510-21-0 is a high-purity cholesterol derivative where a hemisuccinate ester group is introduced to the sterol structure. This chemical modification is critical for enhancing solubility and reactivity, making it a versatile intermediate in advanced synthesis. It is primarily sought after by research institutions and pharmaceutical manufacturers for developing novel drug delivery systems, biomaterials, and as a key precursor in steroid chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of liposomal drug carriers, prodrugs, and other advanced therapeutic agents.
• Biomaterial Research: Used in the development of biocompatible polymers, hydrogels, and surface-modifying agents for medical devices.
• Liposome & Nanoparticle Formulation: Serves as a functional lipid component to create stable, targeted delivery vesicles for genes and drugs.
• Steroid Chemistry: An important precursor for the chemical modification of steroids to alter their biological activity and pharmacokinetic properties.
• Bioconjugation: Utilized to attach cholesterol moieties to peptides, proteins, or other molecules to improve membrane association.
• Reference Standard: Employed as an analytical standard in quality control and research laboratories for method development and validation.

Basic Information

Product Name	Cholesteryl Hemisuccinate
CAS No.	1510-21-0
Molecular Formula	C31H50O4
Molecular Weight	486.73 g/mol
Synonyms	Cholesterol hemisuccinate; Cholesteryl hydrogen succinate; 3β-Hydroxy-5-cholesten-3-yl hydrogen succinate; NSC 35753; Cholest-5-en-3β-ol hemisuccinate; 5-Cholesten-3β-ol hemisuccinate; Succinic acid mono(cholesteryl) ester
EINECS	Contact for details

Quality Control

Our Cholesteryl Hemisuccinate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 155 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.