Description

2-Fluoro-Hypoxanthine is a fluorinated purine nucleobase analog, a key building block in medicinal chemistry and life science research. This compound is valued for its role as a versatile intermediate in the synthesis of modified nucleosides and nucleotides, which are crucial for developing antiviral and anticancer agents. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on nucleic acid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs for antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate purine metabolism and related pathways.
• Probe Development: Serves as a building block for creating fluorescent or radiolabeled probes for molecular biology and diagnostic applications.
• Antiviral Agent Synthesis: Incorporated into the structure of experimental compounds targeting viral polymerases.
• Nucleic Acid Chemistry: Employed in the study of DNA/RNA structure and function, exploring the effects of fluorine substitution on base pairing and stability.
• Library Synthesis: Used in combinatorial chemistry for generating diverse libraries of purine-based compounds for high-throughput screening.

Basic Information

Product Name	2-Fluoro-Hypoxanthine
CAS No.	1480-90-6
Molecular Formula	C5H3FN4O
Molecular Weight	154.10 g/mol
Synonyms	2-Fluorohypoxanthine; 2-Fluoro-1H-purin-6(9H)-one; 2-Fluoro-9H-purin-6-ol; 6-Hydroxy-2-fluoropurine; 2-Fluoropurine-6-ol; 2-F-6-Hypoxanthine; 2-Fluoropurine-6(1H)-one
EINECS	Contact for details

Quality Control

Our 2-Fluoro-Hypoxanthine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.