Description

17-β-Estradiol 3-Methyl Ether is a high-purity synthetic steroid derivative, specifically the 3-methyl ether of the primary female sex hormone estradiol. This compound is a critical pharmaceutical intermediate and research chemical, valued for its enhanced metabolic stability compared to the parent hormone. It is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and life sciences sectors developing hormone therapies, reference standards, and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of steroidal drugs and hormone replacement therapies (HRT).
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control testing of pharmaceutical products.
• Biochemical Research: Employed in studies of estrogen receptor binding, hormone metabolism, and endocrinology research.
• Veterinary Medicine: Utilized in the development of hormonal treatments for animals.
• Academic Research: Serves as a reagent in university and institutional research projects focused on steroid chemistry and biology.

Basic Information

Product Name	17-β-Estradiol 3-Methyl Ether
CAS No.	1474-53-9
Molecular Formula	C19H26O2
Molecular Weight	286.41 g/mol
Synonyms	Estradiol 3-Methyl Ether; 3-Methoxyestra-1,3,5(10)-trien-17β-ol; 17β-Estradiol 3-methyl ether; Estrone 3-methyl ether (related); 3-Methoxy-17β-estradiol; 3-ME2; 3-Methoxyestradiol (Note: 3-Methoxyestradiol typically refers to the 17β-hydroxy form); 3-O-Methylestradiol
EINECS	Contact for details

Quality Control

Our 17-β-Estradiol 3-Methyl Ether is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards suitable for pharmaceutical development and research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.