Description

Sodium [5-(2,4-Dioxopyrimidin-1-Yl)-3,4-Dihydroxyoxolan-2-Yl]Methyl Phosphono Phosphate is a high-purity nucleotide derivative, specifically a sodium salt of a modified uridine diphosphate analog. This compound is critical for advanced biochemical research and pharmaceutical development, serving as a key building block or intermediate. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in nucleotide-based drug discovery, enzyme studies, and molecular biology applications.

Application

• Pharmaceutical Intermediate: Acts as a crucial precursor in the synthesis of novel nucleoside-based therapeutics, including antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases, polymerases, and other nucleotide-processing enzymes.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents for molecular diagnostics and high-throughput screening assays.
• Proteomics & Metabolomics: Serves as a standard or tracer compound in mass spectrometry-based metabolic pathway analysis.
• Enzyme Cofactor Studies: Utilized to investigate the mechanism of action of enzymes that utilize nucleotide cofactors.
• Academic Research: A valuable tool for universities and research institutes studying cell signaling, DNA/RNA metabolism, and glycosylation processes.

Basic Information

Product Name	Sodium [5-(2,4-Dioxopyrimidin-1-Yl)-3,4-Dihydroxyoxolan-2-Yl]Methyl Phosphono Phosphate
CAS No.	1457-11-0
Molecular Formula	C10H13N2Na2O13P2 (or similar salt form) *
Molecular Weight	Contact for details
Synonyms	Sodium UDP analog; Uridine 5'-diphospho-2'-methylenephosphonate sodium salt; 2'-C-Methyl-uridine-5'-diphosphate disodium salt; UDP-2'-C-methylenephosphonate disodium; 1-[(2R,3S,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione sodium salt
EINECS	Contact for details

* Exact salt stoichiometry may vary. Contact us for the specific molecular formula of the supplied grade.

Quality Control

Our Sodium [5-(2,4-Dioxopyrimidin-1-Yl)-3,4-Dihydroxyoxolan-2-Yl]Methyl Phosphono Phosphate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Anhydrous basis)
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.