Description

(5α)-Pregnane-3,20-Dione Cyclic 20-(1,2-Ethanediyl Acetal) CAS NO 1452-23-9 is a high-purity steroid intermediate featuring a protected ketone functional group. This compound is critically important for its role as a versatile building block in the multi-step synthesis of complex pharmaceutical actives and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing steroid-based therapeutics and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various steroid-based drugs, including corticosteroids, progestins, and other hormonal agents.
• Organic Synthesis Building Block: Utilized in research and development for constructing complex molecular architectures, leveraging its protected diketone functionality for selective reactions.
• Biochemical Research: Serves as a reference standard or starting material in metabolic pathway studies and steroid biochemistry research.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals where precise stereochemistry and functional group manipulation are required.

Basic Information

Product Name	(5α)-Pregnane-3,20-Dione Cyclic 20-(1,2-Ethanediyl Acetal)
CAS No.	1452-23-9
Molecular Formula	C23H36O3
Molecular Weight	360.54 g/mol
Synonyms	20,20-Ethylenedioxy-5α-pregnane-3-one; 5α-Pregnane-3,20-dione cyclic 20-ethylene acetal; 3-Oxo-5α-pregnane-20-carboxaldehyde ethylene acetal; 20,20-Ethylenedioxy-3-oxo-5α-pregnane; Pregnane-3,20-dione cyclic ethylene ketal (5α-); NSC 523777
EINECS	Contact for details

Quality Control

Our (5α)-Pregnane-3,20-Dione Cyclic 20-(1,2-Ethanediyl Acetal) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.