Description

Cholestane-3β,5α,6β-Triol is a high-purity sterol derivative, specifically a trihydroxylated cholestane, with the CAS registry number 1253-84-5. This compound serves as a critical reference standard and key synthetic intermediate in advanced pharmaceutical and biochemical research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of steroid-based therapeutics, metabolic pathway studies, and analytical method validation.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of sterols and related metabolites in drug development and quality control (QC/QA) laboratories.
• Biochemical Research: Serves as a precursor or intermediate in the synthesis of more complex steroid hormones and their analogs for biological activity studies.
• Metabolic Pathway Investigation: Employed as a tool compound to study cholesterol metabolism, oxidation pathways, and related enzymatic processes.
• Analytical Chemistry: Functions as a critical calibration standard in chromatographic methods (HPLC, GC) and spectroscopic analysis for accurate compound identification.
• Fine Chemical Synthesis: Acts as a building block for the custom synthesis of specialized sterol derivatives for research and development purposes.

Basic Information

Product Name	Cholestane-3β,5α,6β-Triol
CAS No.	1253-84-5
Molecular Formula	C27H48O3
Molecular Weight	420.67 g/mol
Synonyms	3β,5α,6β-Cholestanetriol; 5α-Cholestane-3β,5,6β-triol; (3β,5α,6β)-Cholestane-3,5,6-triol; Cholestanetriol; 3β,5α,6β-Trihydroxycholestane; NSC 169016; 1253-84-5
EINECS	Contact for details

Quality Control

Our Cholestane-3β,5α,6β-Triol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.