Description

Cholesterol-5Alpha,6Alpha-Epoxide is a specific oxidized derivative of cholesterol, formed through the epoxidation of the 5,6-double bond. This compound is of significant interest as a key intermediate and reference standard in biochemical and pharmaceutical research, particularly in studies related to cholesterol metabolism and oxidative stress pathways. It is essential for researchers and manufacturers in the life sciences, pharmaceutical development, and analytical chemistry sectors who require high-purity biochemical intermediates.

Application

• Biochemical Research Intermediate: Serves as a critical precursor in the synthesis of more complex oxysterols and other sterol derivatives for metabolic studies.
• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and analytical method development of sterol-based pharmaceuticals.
• Oxidative Stress Studies: Employed as a model compound to investigate the biological effects and pathways of cholesterol oxidation products in cellular systems.
• Analytical Chemistry: Utilized as a standard for calibrating instruments (e.g., HPLC, GC-MS) in the quantification of sterols and their metabolites in various matrices.
• Academic & Institutional Research: Provides a well-defined chemical tool for universities and research institutes exploring lipid biochemistry, atherosclerosis, and related disease mechanisms.

Basic Information

Product Name	Cholesterol-5Alpha,6Alpha-Epoxide
CAS No.	1250-95-9
Molecular Formula	C27H46O2
Molecular Weight	402.66 g/mol
Synonyms	5α,6α-Epoxycholestan-3β-ol; 5,6α-Epoxycholesterol; Cholest-5-en-3β-ol, 5,6-epoxide, (5α,6α)-; 5α,6α-Epoxycholesterol; 3β-Hydroxy-5α,6α-epoxycholestane; Cholesterol α-epoxide; 5,6-Epoxy-5α-cholestan-3β-ol
EINECS	215-015-6

Quality Control

Our Cholesterol-5Alpha,6Alpha-Epoxide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and related substances is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.