Description

Azacosterol Dihydrochloride is a steroidal compound of significant interest in biochemical and pharmaceutical research. Its value lies in its role as a specific inhibitor of cholesterol biosynthesis, making it a crucial tool for studying lipid metabolism and related cellular pathways. This product is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors, particularly those focused on cardiovascular disease, metabolic disorders, and novel therapeutic agent discovery.

Application

• Biochemical Research: Used as a potent and specific inhibitor of the enzyme δ24-reductase in the cholesterol biosynthesis pathway.
• Pharmaceutical Development: Serves as a key reference standard and pharmacological tool in the discovery of drugs targeting hypercholesterolemia and atherosclerosis.
• Cell Biology Studies: Employed to manipulate cellular cholesterol levels and investigate its role in membrane fluidity, signal transduction, and cell proliferation.
• Metabolic Pathway Analysis: A critical compound for elucidating the late stages of sterol biosynthesis in various biological systems.
• Academic & Institutional Research: Fundamental for university and institutional labs conducting advanced studies in lipidology and metabolic diseases.

Basic Information

Product Name	Azacosterol Dihydrochloride
CAS No.	1249-84-9
Molecular Formula	C27H48N2O • 2HCl
Molecular Weight	489.6 g/mol (for free base C27H48N2O)
Synonyms	20,25-Diazacholesterol Dihydrochloride; 22,26-Imino-5α-cholestan-3β-ol Dihydrochloride; Azacosterol HCl; SC-12937; 25-Azacholesterol Dihydrochloride; δ24(25)-Sterol Reductase Inhibitor; 22,26-Azacholestanol Dihydrochloride
EINECS	Contact for details

Quality Control

Our Azacosterol Dihydrochloride is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.