Description

1,3,5[10]-Estratrien-3-Ol-17-One Sulfate Potassium Salt is a chemically defined steroid sulfate salt, a key intermediate in the synthesis of various steroidal pharmaceuticals and active pharmaceutical ingredients (APIs). This high-purity compound is critical for ensuring batch-to-batch consistency and regulatory compliance in advanced manufacturing processes. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development and production of hormone-based therapies and diagnostic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of steroidal drugs, including estrogens and related hormone therapies.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies, receptor binding assays, and endocrine research.
• API Development: Serves as a starting material or intermediate in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Analytical Standard: Employed in quality control laboratories for method development, calibration, and verification in HPLC, LC-MS, or other analytical techniques.
• Veterinary Pharmaceuticals: Used in the formulation of specific hormone treatments for animal health applications.

Basic Information

Product Name	1,3,5[10]-Estratrien-3-Ol-17-One Sulfate Potassium Salt
CAS No.	1240-04-6
Molecular Formula	C18H21KO5S
Molecular Weight	388.52 g/mol
Synonyms	Estrone Potassium Sulfate; Estrone 3-Sulfate Potassium Salt; 3-Hydroxyestra-1,3,5(10)-trien-17-one 3-sulfate potassium salt; Estrone 3-sulphate potassium salt; 17-Oxoestra-1,3,5(10)-trien-3-yl sulfate potassium salt; E1S Potassium Salt; Estrone Sulfate K+ Salt
EINECS	Contact for details

Quality Control

Our 1,3,5[10]-Estratrien-3-Ol-17-One Sulfate Potassium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.