Description

6Beta-Hydroxyestrone is a key hydroxylated metabolite of the primary estrogen, estrone. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in estrogen metabolism and potential biological activity. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector, particularly for analytical method development and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, GC-MS) in drug metabolism and pharmacokinetics (DMPK) studies.
• Biochemical Research: Essential for investigating the metabolic pathways and biological effects of endogenous estrogens and their derivatives.
• Diagnostic Kit Development: Employed as a key component in the development and validation of immunoassays and diagnostic tests for hormonal analysis.
• Academic & Clinical Studies: Supports research into endocrine function, hormone-related diseases, and the development of novel therapeutic agents.
• Metabolite Synthesis: Acts as a valuable synthetic intermediate or precursor for the preparation of other specialized steroid metabolites.

Basic Information

Product Name	6Beta-Hydroxyestrone
CAS No.	1229-25-0
Molecular Formula	C18H22O3
Molecular Weight	286.36 g/mol
Synonyms	6β-Hydroxyestrone; 6β-Hydroxy-1,3,5(10)-estratrien-3-ol-17-one; 6β-Hydroxyoestrone; Estrone, 6β-hydroxy-; 1,3,5(10)-Estratrien-3-ol-17-one, 6β-hydroxy-; 6β-Hydroxyestra-1,3,5(10)-trien-3-ol-17-one
EINECS	Contact for details

Quality Control

Our 6Beta-Hydroxyestrone is produced and tested under a rigorous quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.