Description

5B-Androstane-3,17-Dione is a key steroid intermediate and reference standard of significant importance in pharmaceutical research and development. This compound serves as a crucial building block for the synthesis of more complex steroid hormones and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in steroid chemistry, metabolic studies, and analytical method development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of various steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and steroidogenesis research.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for method validation, quality control, and calibration in HPLC, GC-MS, and other analytical techniques.
• Metabolite Standard: Essential for the identification and quantification of endogenous steroid metabolites in clinical and diagnostic testing.
• Fine Chemical Synthesis: Employed as a starting material or intermediate for custom synthesis and the production of specialized steroid derivatives.

Basic Information

Product Name	5B-Androstane-3,17-Dione
CAS No.	1229-12-5
Molecular Formula	C19H28O2
Molecular Weight	288.42 g/mol
Synonyms	5β-Androstane-3,17-dione; Etiocholane-3,17-dione; 3,17-Etiocholanedione; 5β-Androstanedione; NSC 97199; 17-Oxo-5β-androstan-3-one; 3,17-Dioxo-5β-androstane
EINECS	214-969-0

Quality Control

Our 5B-Androstane-3,17-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and residual solvent analysis to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.