Description

1,3,5(10)-Estratrien-3-Ol-16,17-Dione is a high-purity steroid derivative and a key synthetic intermediate in pharmaceutical research and development. This compound is valued for its precise chemical structure, which serves as a crucial building block for the synthesis of more complex steroidal active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of hormone-related therapies and novel steroidal compounds, where reliable quality and consistent supply are paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs and hormones.
• Research & Development: Used in academic and industrial laboratories for investigating steroidal pathways and developing new therapeutic agents.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Studies: Employed in studies exploring enzyme interactions and metabolic pathways involving steroid backbones.
• Fine Chemical Synthesis: A building block for creating specialized, high-value steroidal compounds for various applications.

Basic Information

Product Name	1,3,5(10)-Estratrien-3-Ol-16,17-Dione
CAS No.	1228-73-5
Molecular Formula	C18H22O3
Molecular Weight	286.36 g/mol
Synonyms	16,17-Diketoestradiol; 16,17-Dioxoestra-1,3,5(10)-trien-3-ol; Estra-1,3,5(10)-triene-3,16,17-triol-16,17-dione; 3-Hydroxyestra-1,3,5(10)-triene-16,17-dione; Estradiol-16,17-dione
EINECS	Contact for details

Quality Control

Our 1,3,5(10)-Estratrien-3-Ol-16,17-Dione is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.