Description

17-Epiestriol is a stereoisomer of the naturally occurring estrogen hormone estriol, distinguished by the orientation of the hydroxyl group at the C17 position. This specific configuration makes it a valuable reference standard and a key intermediate in pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for analytical, diagnostic, and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of estrogens in drug substances and finished products via HPLC, GC, or LC-MS.
• Biochemical Research: Serves as a critical tool in studying estrogen receptor (ER) binding affinity, metabolic pathways, and hormonal activity.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key building block in the synthetic pathways of steroidal drugs and hormone therapies.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration kits and immunoassays for clinical hormone level testing.
• Academic & Institutional Research: Supports fundamental research in endocrinology, oncology, and developmental biology.

Basic Information

Product Name	17-Epiestriol
CAS No.	1228-72-4
Molecular Formula	C18H24O3
Molecular Weight	288.38 g/mol
Synonyms	16,17-Epiestriol; Estra-1,3,5(10)-triene-3,16α,17β-triol; 16α-Hydroxy-17β-estradiol; 16-epi-Estriol; NSC 9894; 17-epi-Oestriol
EINECS	214-950-1

Quality Control

Our 17-Epiestriol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.