Description

(9β)-3-Hydroxyestra-1,3,5(10)-Trien-17-One CAS NO 1225-03-2 is a high-purity steroid derivative, specifically a hydroxy ketone derivative of the estrane series. This compound is a critical intermediate in the synthesis of various steroidal pharmaceuticals and active pharmaceutical ingredients (APIs). It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers requiring a reliable, high-quality building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of steroidal hormones and related therapeutic agents.
• Research & Development: Used in academic and industrial R&D for studying steroid metabolism, receptor binding, and developing new drug candidates.
• Reference Standard: Serves as a certified reference material (CRM) or analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in studies related to endocrinology, enzymology, and metabolic pathways involving steroid transformations.
• Fine Chemical Synthesis: Utilized as a specialized building block for the production of complex, high-value organic molecules in fine chemical manufacturing.

Basic Information

Product Name	(9β)-3-Hydroxyestra-1,3,5(10)-Trien-17-One
CAS No.	1225-03-2
Molecular Formula	C₁₈H₂₄O₂
Molecular Weight	272.38 g/mol
Synonyms	9β-Hydroxy-4-estrene-3,17-dione; 9β-Hydroxyestr-4-ene-3,17-dione; 9β-Hydroxy-19-norandrost-4-ene-3,17-dione; 3-Hydroxyestra-1,3,5(10)-trien-17-one, (9β)-; 9β-Hydroxyestra-1,3,5(10)-trien-17-one; 9β-Hydroxy-1,3,5(10)-estratrien-17-one; 9β-Hydroxy-δ¹,³,⁵(¹⁰)-estratrien-17-one
EINECS	Contact for details

Quality Control

Our (9β)-3-Hydroxyestra-1,3,5(10)-Trien-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by FT-IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.