Description

6-Methylthioguanine is a purine derivative and a key biochemical intermediate with significant research and development applications. This compound is valued for its role in the study of nucleic acid metabolism and as a building block for more complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery and biochemical synthesis.

Application

• Pharmaceutical Research & Development: Serves as a crucial intermediate in the synthesis of novel therapeutic agents, particularly in oncology and antiviral drug discovery programs.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic studies to investigate pathways related to purine metabolism and nucleic acid synthesis.
• Nucleoside/Nucleotide Analog Synthesis: Acts as a precursor for the development of modified nucleosides with potential biological activity.
• Life Science Reagents: Incorporated into specialized kits and reagents for molecular biology and diagnostic assay development.
• Academic Research: Employed in university and institutional laboratories for fundamental research in chemistry and biochemistry.

Basic Information

Product Name	6-Methylthioguanine
CAS No.	1198-47-6
Molecular Formula	C6H7N5S
Molecular Weight	181.22 g/mol
Synonyms	6-(Methylthio)guanine; 2-Amino-6-methylmercaptopurine; 6-Methylmercaptoguanine; 6-MTG; NSC 407347; 6-Methylthio-2-aminopurine; 2-Amino-6-(methylthio)purine; Guanine, 6-methylthio-
EINECS	214-843-6

Quality Control

Our 6-Methylthioguanine is produced under a rigorous quality management system to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.